Elevating Renal Impairment Care Through Advanced Clinical Trials
Advancing Understanding
of Kidney Disease
At CRS, our dedicated focus on advancing treatments for renal impairment through specialized early phase clinical trials includes complex pharmacokinetic (PK) and pharmacodynamic (PD) designs tailored for patients with conditions such as end stage renal disease (ESRD) and those undergoing dialysis.
Managing approximately eight trials annually, each lasting four to six months, we oversee dose titration, various drug formulations, routes of administration, and both blinded and unblinded designs. With meticulous trial planning and execution, our team ensures high-quality outcomes that significantly enhance patient care.
Robust Recruitment and Accredited Lab Support
CRS leverages a robust database and extensive network of nephrologists and dialysis centers to expedite the recruitment of volunteers and patients with renal impairment. Collaborations with university hospital nephrology departments and dialysis centers provide access to specialized facilities, including hospital beds for dialysis. Additionally, CRS partners with LKF – Laboratorium für Klinische Forschung GmbH, an accredited medical lab specializing in clinical trial support. Their rapid turnaround time of laboratory results supports efficient screening and safety monitoring of trial participants, ensuring the reliability and efficiency of our trials.
Our Renal Assessment Techniques
- Estimated glomerular filtration rate (eGFR)
- Renal plasma flow rate
- Urinary output and electrolyte/creatinine excretion
- Cystatin C (CysC)
- Osmolarity
- Iohexol
- Pharmacokinetic assessments during dialysis
Patient-centered Renal Impairment Research
Join us in our commitment to patient safety and improving health through advancing renal impairment research. Our experienced team of scientists, project managers, and medical writers will collaborate with you on study design, protocol development, and the communication of findings that directly impact patient outcomes. Partner with us to advance solutions for kidney health and achieve your clinical trial objectives with our patient-centered approach and expertise.
Reach out today to contribute to significant discoveries that benefit patients worldwide.