Exploring New Frontiers In Metabolic Research
Our expertise spans from pioneering research to clinical
trials, advancing therapies for complex metabolic
disorders. Join us in shaping the future of
metabolic health.
Understanding Metabolic Disorders
Metabolic disorders like obesity, metabolic syndrome, and diabetes are major contributors to global cardiometabolic morbidity and mortality. We specialize in developing innovative treatments, leveraging our specialized expertise and extensive experience to tackle these critical health challenges.
Our Methodologies
Food Consumption
Standardized Meal Tests, Quantification of Ad Libitum Food Intake, Hunger and Satiety Assessments, Consumption and Eating Behavior Questionnaires, and Food Diaries.
Fat Tissue Assessment
Body Impedance Measurement, Subcutaneous Fat Biopsies, and Liver Fat Content Evaluation (Fibro Scan®, MRI-PDFF).
Insulin Resistance Assessment
HOMA-IR, Quicki Index, Standardized Test Meals, Oral Glucose Tolerance Test (OGTT), Intravenous Glucose Tolerance Test (IVGTT), and Euglycemic Glucose Clamp Tests (M-value).
Biomarker Analysis
Adipokines (Adiponectin, Leptin, Visfatin, Resistin), and Cytokines (TNF-alpha, Interleukin-6 (IL-6), Interleukin-1ß (IL-1ß)).
Bridging Preclinical Research to Clinical Trials
At CRS, we excel in translating preclinical evidence into impactful proof-of-concept studies for new metabolic therapies. Our approach seamlessly integrates a robust proprietary database of volunteers and patients with a network of medical specialists, ensuring efficient recruitment and adherence to FDA and EMA regulatory standards.
Our Commitment To Scientific Excellence
Scientific excellence is at the core of our operations. Our multidisciplinary team of scientists, project managers and medical writers collaborates closely to support every stage of study design, protocol development, report finalization, and manuscript preparation. This dedication to rigorous scientific standards is underscored by our extensive publication record in international peer-reviewed journals.
Partner with us to advance metabolic disorder research and discover how our expertise can drive innovation and improve patient outcomes on a global scale.